EurekAlert!

Histone acetylation and transcription factor dynamics lay the groundwork for gene expression in brain development

Researchers from Osaka University find that neuronal activity induces gene expression at the preprepared histone acetylation sites in the nucleus by influencing transcription factors and chromatin ...
ascopubs.org

Development and initial clinical testing of a multiplex assay evaluating histone modifier p300 acetylation in prostate cancer circulating tumor cells.

Longitudinal variability in symptom burden for patients with prostate cancer (PC). This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not include a full text ...
The Scientist

The Histone Code

What is the histone code? Different chemical marks, such as acetylation, methylation, or phosphorylation, are made to numerous residues on the N-terminal tails of histone proteins. Some posit that ...
The Scientist

Histone Modification Types and Effects

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
C&EN

Expanding the histone code

Strands of DNA wrapped around a histone. Credit: Molekuul/Science Source Histones are among the most abundant proteins in the body. They act as spools that help compact DNA so our enormous genomes ...